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Recent Research on Aspirin as a Treatment for Alzheimer’s

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Approximately 10 percent of adults aged 65 or older are living with Alzheimer’s disease, and the number is expected to dramatically increase in the next few decades. There are very few medications available for seniors with Alzheimer’s, and the formulations offer limited effectiveness. However, research remains ongoing.

Aging adults with Alzheimer’s disease can benefit from receiving professional Alzheimer’s care. Henderson seniors need regular mental stimulation when managing memory-related conditions, and a reliable in-home caregiver who has extensive training in Alzheimer’s care can be a great asset.

Scientists from Rush University Medical Center discovered that common aspirin may offer hope for older adults with Alzheimer’s disease. Here is what you need to know about this research.

The Relationship Between Alzheimer’s and Aspirin

Researchers now know that Alzheimer’s disease is caused by the body’s inability to remove amyloid beta proteins. These proteins adhere to neurons where they clump and tangle, which causes cell damage and death. During the process, the communication between neurons gradually decreases, which causes cognitive and physical symptoms.

One of the best ways to fight Alzheimer’s disease is to stimulate the cellular and chemical processes that remove excess proteins from the brain. Aspirin stimulates peroxisome proliferator-activated receptor a, or PPARA. The receptors then boost the effects of a protein known as TFEB, which triggers organelles known as lysosomes. These organelles are responsible for breaking down amyloid protein molecules so they can be removed as waste.

The study involved administering aspirin to a group of laboratory mice genetically altered to develop Alzheimer’s disease. After one month, the mice were reevaluated for levels of amyloid beta plaque formations in the brain. The scientists discovered that the mice receiving the oral aspirin had fewer amyloid plaques compared to the mice that did not receive the over-the-counter medication.

Researchers plan to investigate further. However, the findings suggest aspirin may be useful in the fight against Alzheimer’s disease and other types of dementia.

Aspirin’s Additional Benefits

Aspirin reduces the rate of blood clotting to prevent heart attacks and strokes. The non-steroidal anti-inflammatory drug is also helpful in reducing the processes that contribute to inflammation. When the immune system responds to a perceived threat, certain white blood cells and chemical compounds are released in an attempt to eliminate the contaminant, which creates an inflammatory response. A similar response occurs when neurons begin undergoing trauma.

If your senior loved one has been diagnosed with a serious condition and needs help with tasks like meal prep, transportation, bathing, and grooming, reach out to Home Care Assistance, a leading provider of home care Henderson, NV, families can trust. We also offer comprehensive care for seniors with dementia, Alzheimer’s, and Parkinson’s.

The University of York Study

A group of scientists from the University of York questioned the safety of habitually taking aspirin. When taken long-term, aspirin is known to cause gastrointestinal symptoms such as ulceration and hemorrhage. Two studies involved administering aspirin to seniors with Alzheimer’s. Up to 4.6 percent of the people receiving aspirin developed hemorrhages in the brain. The control group who did not receive aspirin experienced no ill effects.

Caring for older adults with Alzheimer’s disease can be an overwhelming responsibility. Families who find it difficult to care for their aging loved ones without assistance can benefit greatly from professional respite care. Henderson, NV, family caregivers who need a break from their caregiving duties can turn to Home Care Assistance. Using our proprietary Balanced Care Method, our respite caregivers can encourage your loved one to eat well, exercise regularly, get plenty of mental and social stimulation, and focus on other lifestyle factors that promote longevity. Call us at (702) 527-7723 to schedule a free in-home consultation.

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